Invention, Preparation and Application of acetyl hydrazine derivatives of hyperpiperazine (SM-1)
The invention relates to a novel derivatives of hyperpiperazine acetyl hydrazine class. The hyperpiperazine acetyl hydrazine derivatives of the present invention have effective anti-tumor activity.
Preparation of 4- benzyl piperazine ethyimide (imide methyl benzene) hydrazine compounds
The present invention relates to a preparation method of 4-benzyl piperazine ethylenimide hydrazine compound, which includes several specific steps. The method is safe, simple and easy to operate.
Preparation and application of recombinant adeno-associated virus vectors
The invention relates to a recombinant adeno-associated virus vector and its preparation and application. The recombinant adeno-associated virus vector of the invention has obvious anti-tumor effect and little toxic and side effect, and has a good application prospect.
Piperazine or hyperpiperazine oxalohydrazide compounds and their preparation methods and applications
The present invention relates to a novel class of piperazine or hyperpiperazine oxalohydrazine compound. Piperazine or hyperpiperazine oxalohydrazide compounds of the present invention have effective anti-tumor activity.
Derivatives of hyperpiperazine acetyl hydrazine with low neurotoxicity and their preparation methods and applications
The invention relates to a derivative compound of hyperpiperazine acetylhydrazine class. The compounds in the present invention can selectively kill some cancer cells and have strong anticancer activity, with greatly reduced neurotoxicity and broad prospects for clinical application.
The invention relates to a benzene sulfonyl or benzoyl piperazine compound and a preparation method and application thereof
The invention relates to a benzene sulfonyl or benzoyl piperazine compound. The compound has an effective anticancer activity and is characterized by low toxicity.
Obitazine-fumarate, hydrate, crystal type and preparation method
The invention belongs to the field of pharmaceutical chemistry and provides a possibility for providing higher pharmaceutical effect, easier preparation and better storage stability of obitazine-Fumarate.
4-benzyl piperinethimide (imide methyl benzene) hydrazine compounds, their preparation methods and drug combinations
This application relates to 4-benzyl piperimethylhydrazide compounds, their preparation methods, pharmaceutical compositions and USES. In vivo and in vitro cell experiments in animals have proved that the compound can be used in the treatment of cancer.
Azacyclosubstituted hydrazide compounds and their preparation methods and applications
The invention relates to azacyclosubstituted hydrazide compounds and a preparation method and application thereof. The compound can selectively kill some cancer cells, has strong anticancer activity and can inhibit tumor growth.
The utility model relates to a tumor-targeting adeno-associated virus vector with a double gene
The present invention relates to a double-gene recombinant adeno-associated virus vector targeting tumors, in particular to a recombinant adeno-associated virus vector containing both Caspase3 and endostatin with the reverse connection of the large and small subunits, a preparation method thereof and its use against tumors.
The invention discloses an AAV vector for the treatment of type 2 diabetes mellitus, and a preparation method and application thereof
The invention discloses an AAV carrier for the treatment of type 2 diabetes and a preparation method and application thereof. The AAV vector has a long time to express the exogenous gene GLP-1, and the expression stability is good, which can effectively treat type 2 diabetes.
A globin gene and its recombinant adeno-associated virus vector
The invention discloses a human beta globin gene containing a human beta globin gene promoter and a recombinant adeno-associated virus vector containing it. The recombinant vector has high transfection efficiency and can be used for gene therapy of thalassemia.
