深圳市真兴医药技术有限公司

The invention relates to a recombinant adeno-associated virus vector and its preparation and application. The recombinant adeno-associated virus vector of the invention has obvious anti-tumor effect and little toxic and side effect, and has a good application prospect.

The present invention relates to a double-gene recombinant adeno-associated virus vector targeting tumors, in particular to a recombinant adeno-associated virus vector containing both Caspase3 and endostatin with the reverse connection of the large and small subunits, a preparation method thereof and its use against tumors.

The invention discloses an AAV carrier for the treatment of type 2 diabetes and a preparation method and application thereof. The AAV vector has a long time to express the exogenous gene GLP-1, and the expression stability is good, which can effectively treat type 2 diabetes.